Tert-butyldimethyl((4-(prop-1-yn-1-yl)benzyl)oxy)silane → Tert-butyldimethyl((4-propylbenzyl)oxy)silane

反応式

[C:1]([Si:5]([CH3:18])([CH3:17])[O:6][CH2:7][C:8]1[CH:13]=[CH:12][C:11]([C:14]#[C:15][CH3:16])=[CH:10][CH:9]=1)([CH3:4])([CH3:3])[CH3:2].[H][H]>C(OCC)(=O)C.[Pd]>[C:1]([Si:5]([CH3:18])([CH3:17])[O:6][CH2:7][C:8]1[CH:13]=[CH:12][C:11]([CH2:14][CH2:15][CH3:16])=[CH:10][CH:9]=1)([CH3:3])([CH3:4])[CH3:2]

参加物

実験手順

tert-butyldimethyl((4-(prop-1-yn-1-yl)benzyl)oxy)silane (252 mg, 0.968 mmol) was dissolved in 20 mL of ethyl acetate, and then passed through H-Cube apparatus equipped with 10% Pd/C catridge under 20 bar of hydrogen pressure at a speed of 0.5 mL/min. The solution thus passed was concentrated by distillation under reduced pressure to obtain 251 mg (0.949 mmol, 98%) of the desired compound.