Formamide → HCID 178518013、化合物
反応式
[NH2:1][C:2]1[CH:10]=[CH:9][C:8]([I:11])=[CH:7][C:3]=1[C:4](O)=[O:5].[CH:12]([NH2:14])=O>O>[I:11][C:8]1[CH:7]=[C:3]2[C:2](=[CH:10][CH:9]=1)[N:1]=[CH:12][N:14]=[C:4]2[OH:5]参加物
4
反応条件
- 温度
- 190 °C
実験手順
A mixture of 2-amino-5-iodobenzoic acid (125 g, 475 mmol) and formamide (200 mL) was heated to 190° C. for 2 hours. After cooling to room temperature, the reaction mixture was poured into water (500 mL) and stirred for 2 hours. The solids were filtered and dried under high vacuum to provide the product (108 g, 83%).
後処理
- temperatureAfter cooling to room temperature
- filtrationThe solids were filtered
- customdried under high vacuum
出典と根拠
- ORDレコード
- ord-1cf203d6a8f34d2ea4d9ba40e1884b22
- 出典データセット
- uspto-grants-2014_02
- 特許番号
- US08648087B2
反応ノート
読み込み中…