Methyl iodide → 2-Hexyl-1-methyl-1H-indole
反応式
[CH2:1]([C:7]1[NH:8][C:9]2[C:14]([CH:15]=1)=[CH:13][CH:12]=[CH:11][CH:10]=2)[CH2:2][CH2:3][CH2:4][CH2:5][CH3:6].[OH-].[K+].I[CH3:19].[Cl-].[NH4+]>CS(C)=O.C(OCC)(=O)C>[CH2:1]([C:7]1[N:8]([CH3:19])[C:9]2[C:14]([CH:15]=1)=[CH:13][CH:12]=[CH:11][CH:10]=2)[CH2:2][CH2:3][CH2:4][CH2:5][CH3:6]参加物
7
実験手順
To a solution of 2-hexyl-1H-indole in DMSO was added KOH at RT and was stirred for 30 minutes. Then to this mixture, iodomethane was added and stirred for 3 hours. The reaction mixture was treated with saturated ammonium chloride and ethyl acetate. The product was purified by column chromatography.
後処理
- stirringstirred for 3 hours
- customThe product was purified by column chromatography
出典と根拠
- ORDレコード
- ord-d8b96c59aed84e00994ef4daf10531d5
- 出典データセット
- uspto-grants-2014_08
- 特許番号
- US08809382B2
反応ノート
読み込み中…