Thionyl Chloride → HCID 53763295、化合物
反応式
[F:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]=[C:9]([CH3:12])[CH2:10]O)=[CH:4][CH:3]=1.S(Cl)([Cl:15])=O>C(Cl)Cl>[Cl:15][CH2:10][C:9]([CH3:12])=[CH:8][C:5]1[CH:6]=[CH:7][C:2]([F:1])=[CH:3][CH:4]=1参加物
4
実験手順
To a solution of 53.6 g (0.32 mole) of 3-(4-fluorophenyl)-2-methyl-2-propen-1-ol in 100 ml methylene chloride was added dropwise a solution of 57.1 g (0.48 mole) of thionyl chloride in 100 ml methylene chloride. The reaction mixture was stirred at room temperature for 2 hours, then concentrated by rotary evaporation. The product was checked by NMR, then used crude in the reaction with ammonia.
後処理
- concentrationconcentrated by rotary evaporation
- customin the reaction with ammonia
出典と根拠
- ORDレコード
- ord-6c29132ea07448908abdd8c6ba988416
- 出典データセット
- uspto-grants-1985_01
- 特許番号
- US04495196
反応ノート
読み込み中…