Acetyl chloride → HCID 15599411、化合物
反応式
[O:1]1[C:6]2[CH:7]=[CH:8][C:9]([C:11]3[CH:12]([CH3:18])[CH2:13][C:14](=[O:17])[NH:15][N:16]=3)=[CH:10][C:5]=2[NH:4][CH2:3][CH2:2]1.[C:19](Cl)(=[O:21])[CH3:20]>O1CCCC1>[C:19]([N:4]1[C:5]2[CH:10]=[C:9]([C:11]3[CH:12]([CH3:18])[CH2:13][C:14](=[O:17])[NH:15][N:16]=3)[CH:8]=[CH:7][C:6]=2[O:1][CH2:2][CH2:3]1)(=[O:21])[CH3:20]参加物
4
実験手順
6-(3,4-Dihydro-1,4(2H)-benzoxazin-6-yl)-2,3,4,5-tetrahydro-5-methylpyridazin-3-one was suspended in tetrahydrofuran and one equivalent of acetyl chloride was added. After one half hour at 0° C., the solvent was removed in vacuo, and the product was crystallized from ethanol in 61% yield, mp 185.5°-186° C.
後処理
- waitAfter one half hour at 0° C.
- customthe solvent was removed in vacuo
- customthe product was crystallized from ethanol in 61% yield, mp 185.5°-186° C.
出典と根拠
- ORDレコード
- ord-edc6953ed5ea4efeaec924b9a52eac0d
- 出典データセット
- uspto-grants-1988_01
- 特許番号
- US04721784
反応ノート
読み込み中…