4-Chloroaniline → HCID 9841968、化合物
反応式
[Cl:1][C:2]1[CH:8]=[CH:7][C:5]([NH2:6])=[CH:4][CH:3]=1.Br[C:10]1[C:11](=[O:22])[C:12]2[CH:13]=[CH:14][CH:15]=[N:16][C:17]=2[C:18](=[O:21])[C:19]=1[Br:20]>C(O)C>[Cl:1][C:2]1[CH:8]=[CH:7][C:5]([NH:6][C:10]2[C:11](=[O:22])[C:12]3[CH:13]=[CH:14][CH:15]=[N:16][C:17]=3[C:18](=[O:21])[C:19]=2[Br:20])=[CH:4][CH:3]=1参加物
4
実験手順
CeCl3 (0.1 mmol) as a catalyst and 4 equivalents of 4-chloroaniline (10 mmol) were added to 6,7-dibromo-5,8-quinolindion (10 mmol) dissolved in ethanol (100 ml). The reaction mixture was heated at reflux for 8 hrs. After reading the completion of reaction by TLC, it was cooled, filtered, and recrystallized with ethanol to give redish powder of 6-[(N-4-chlorophenyl)amino]-7-bromo-5,8-quinolidione.
後処理
- temperatureThe reaction mixture was heated
- temperatureat reflux for 8 hrs
- customthe completion of reaction by TLC, it
- temperaturewas cooled
- filtrationfiltered
- customrecrystallized with ethanol
- customto give redish powder of 6-[(N-4-chlorophenyl)amino]-7-bromo-5,8-quinolidione
出典と根拠
- ORDレコード
- ord-1cfd3e85fd6b4d18966748f1e66dcdb5
- 出典データセット
- uspto-grants-2004_11
- 特許番号
- US06818653B1
反応ノート
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