Oxalyl chloride → 9-(4-bromo-butyl)-9H-fluorene-9-carboxylic Acid Chloride

HRID 2415138ノート

反応式

HRID 2415138 の反応式
[Br:1][CH2:2][CH2:3][CH2:4][CH2:5][C:6]1([C:19]([OH:21])=O)[C:18]2[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=2[C:12]2[C:7]1=[CH:8][CH:9]=[CH:10][CH:11]=2.C(Cl)(=O)C([Cl:25])=O>ClCCl.CN(C)C=O>[Br:1][CH2:2][CH2:3][CH2:4][CH2:5][C:6]1([C:19]([Cl:25])=[O:21])[C:18]2[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=2[C:12]2[C:7]1=[CH:8][CH:9]=[CH:10][CH:11]=2

参加物

5

反応物 2

HCID 65578Oxalyl chlorideHCID 107125189-(4-bromobutyl)-9H-fluorene-9-carboxylic acid

生成物 1

HCID 105227589-(4-bromo-butyl)-9H-fluorene-9-carboxylic Acid Chloride

試薬・触媒・溶媒 2

HCID 6228Dimethylformamide触媒HCID 6344Dichloromethane溶媒2 回

実験手順

23 g (0.067 mol) of 9-(4-bromo-butyl)-9H-fluorene-9-carboxylic acid are dissolved in 40 ml dichloromethane and combined with three drops of dimethylformamide and 6.96 ml (0.081 mol) of oxalyl chloride, dissolved in 10 ml dichloromethane, under nitrogen at 0° C. The mixture is stirred for 3 hours at ambient temperature. Then the solvent is removed and the crude product is further reacted without any more purification.

後処理

  1. customThen the solvent is removed
  2. customthe crude product is further reacted without any more purification

出典と根拠

ORDレコード
ord-dab5a5a4b66e4e4ca65c4c24ada4c00d
出典データセット
uspto-grants-2004_11
特許番号
US06818644B1

反応ノート

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