HCID 22640158、化合物 → 1-Biphenyl-4-yl-piperazine

HRID 2415143ノート

反応式

HRID 2415143 の反応式
C([N:8]1[CH2:13][CH2:12][N:11]([C:14]2[CH:19]=[CH:18][C:17]([C:20]3[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=3)=[CH:16][CH:15]=2)[CH2:10][CH2:9]1)C1C=CC=CC=1>CO.[OH-].[Pd+2].[OH-]>[C:17]1([C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)[CH:18]=[CH:19][C:14]([N:11]2[CH2:10][CH2:9][NH:8][CH2:13][CH2:12]2)=[CH:15][CH:16]=1

参加物

4

反応物 1

HCID 22640158HCID 22640158、化合物

生成物 1

HCID 27355131-Biphenyl-4-yl-piperazine

試薬・触媒・溶媒 2

HCID 9942167Palladium hydroxide触媒HCID 887Methanol溶媒

実験手順

A suspension of 12.45 g (0.037 mol) of 1-benzyl-4-biphenyl-4-yl-piperazine and 4 g of palladium hydroxide in 360 ml of methanol is stirred for 6 hours at ambient temperature in a Parr apparatus under a hydrogen pressure of 50 psi. The catalyst is separated off and the filtrate is evaporated down.

後処理

  1. customThe catalyst is separated off
  2. customthe filtrate is evaporated down

出典と根拠

ORDレコード
ord-59a29e27e8a44363bf5f47598bfd299e
出典データセット
uspto-grants-2004_11
特許番号
US06818644B1

反応ノート

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