Lithium Hexamethyldisilazide → 7-{1-[2-(4-methoxycarbonyl-phenyl)-vinyl]-hexyl}-4,4-dimethyl-3,4-dihydro-2H-quinoline-1-carboxylic acid tert-butyl ester

反応式

[CH3:1][O:2][C:3](=[O:17])[C:4]1[CH:9]=[CH:8][C:7]([CH2:10]P(OC)(OC)=O)=[CH:6][CH:5]=1.C[Si]([N-][Si](C)(C)C)(C)C.[Li+].[C:28]([O:32][C:33]([N:35]1[C:44]2[C:39](=[CH:40][CH:41]=[C:42]([CH:45]([CH:51]=O)[CH2:46][CH2:47][CH2:48][CH2:49][CH3:50])[CH:43]=2)[C:38]([CH3:54])([CH3:53])[CH2:37][CH2:36]1)=[O:34])([CH3:31])([CH3:30])[CH3:29]>C1COCC1>[C:28]([O:32][C:33]([N:35]1[C:44]2[C:39](=[CH:40][CH:41]=[C:42]([CH:45]([CH:51]=[CH:10][C:7]3[CH:6]=[CH:5][C:4]([C:3]([O:2][CH3:1])=[O:17])=[CH:9][CH:8]=3)[CH2:46][CH2:47][CH2:48][CH2:49][CH3:50])[CH:43]=2)[C:38]([CH3:53])([CH3:54])[CH2:37][CH2:36]1)=[O:34])([CH3:31])([CH3:30])[CH3:29]