4-Bromo-2-ethenyl-1-fluorobenzene → 4-Bromo-2-ethyl-1-fluorobenzene

HRID 2415256ノート

反応式

HRID 2415256 の反応式
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([F:8])=[C:4]([CH:9]=[CH2:10])[CH:3]=1>C(OCC)(=O)C.[Pd]>[Br:1][C:2]1[CH:7]=[CH:6][C:5]([F:8])=[C:4]([CH2:9][CH3:10])[CH:3]=1

参加物

4

反応物 1

HCID 219339834-Bromo-2-ethenyl-1-fluorobenzene

生成物 1

HCID 226410254-Bromo-2-ethyl-1-fluorobenzene

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 8857Ethyl Acetate溶媒

実験手順

The yellow oil from step A (2.8 g, 10 mmol) was dissolved in Ethyl acetate (200 mL). Palladium-on-carbon (10%, 250 mg) was added and the mixture was hydrogenated under 1 atmosphere until TLC showed complete reaction. The mixture was filtered and the filtrate was concentrated to give an oil. 2.4 g, 87%.

後処理

  1. customreaction
  2. filtrationThe mixture was filtered
  3. concentrationthe filtrate was concentrated
  4. customto give an oil

出典と根拠

ORDレコード
ord-5c9659d2b24b40b89f0b8d48f5bfa4d3
出典データセット
uspto-grants-2004_11
特許番号
US06818663B2

反応ノート

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