Oxalyl chloride → 9-(4-bromo-butyl)-9H-fluorene-9-carboxylic Acid Chloride

HRID 2415843ノート

反応式

HRID 2415843 の反応式
[Br:1][CH2:2][CH2:3][CH2:4][CH2:5][C:6]1([C:19]([OH:21])=O)[C:18]2[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=2[C:12]2[C:7]1=[CH:8][CH:9]=[CH:10][CH:11]=2.C(Cl)(=O)C([Cl:25])=O>ClCCl.CN(C)C=O>[Br:1][CH2:2][CH2:3][CH2:4][CH2:5][C:6]1([C:19]([Cl:25])=[O:21])[C:18]2[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=2[C:12]2[C:7]1=[CH:8][CH:9]=[CH:10][CH:11]=2

参加物

5

反応物 2

HCID 65578Oxalyl chlorideHCID 107125189-(4-bromobutyl)-9H-fluorene-9-carboxylic acid

生成物 1

HCID 105227589-(4-bromo-butyl)-9H-fluorene-9-carboxylic Acid Chloride

試薬・触媒・溶媒 2

HCID 6228Dimethylformamide触媒HCID 6344Dichloromethane溶媒2 回

実験手順

23 g (0.067 mol) of 9-(4-bromo-butyl)-9H-fluorene-9-carboxylic acid are dissolved in 40 ml of dichloromethane, and combined with three drops of dimethylformamide and 6.96 ml (0.081 mol) of oxalyl chloride, dissolved in 10 ml of dichloromethane, under nitrogen at 0° C. The mixture is stirred for 3 hours at ambient temperature. Then the solvent is eliminated and the crude product is reacted further without additional purification.

出典と根拠

ORDレコード
ord-82bb8360e2e54040ba8a7f41f21b61b6
出典データセット
uspto-grants-2004_11
特許番号
US06821967B2

反応ノート

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