HCID 69448738、化合物 → Methyl 3-amino-4-formylbenzoate
反応式
[CH3:1][O:2][C:3](=[O:13])[C:4]1[CH:9]=[CH:8][C:7]([CH2:10][OH:11])=[C:6]([NH2:12])[CH:5]=1>C(Cl)Cl.O=[Mn]=O>[CH3:1][O:2][C:3](=[O:13])[C:4]1[CH:9]=[CH:8][C:7]([CH:10]=[O:11])=[C:6]([NH2:12])[CH:5]=1参加物
4
実験手順
Dissolve 3-amino-4-hydroxymethyl-benzoic acid methyl ester (step (c), 4.2 g, 23.3 mmol) in 125 mL of anhydrous CH2Cl2 and add MnO2 (20.2 g, 232.8 mmol) and stirred at RT. After 5 h, the solution was filtered through Celite and concentrated to afford the title compound as a yellow solid upon drying under vacuum. MS m/z: 180.1 (M+1).
後処理
- filtrationthe solution was filtered through Celite
- concentrationconcentrated
出典と根拠
- ORDレコード
- ord-c1abce607aa34c8b9de0207bd568fb73
- 出典データセット
- uspto-grants-2004_11
- 特許番号
- US06822097B1
反応ノート
読み込み中…