1H-Imidazol-1-ylphenylmethanone → HCID 178499872、化合物

HRID 2417643

反応式

HRID 2417643 の反応式
[C:1]([N:9]1[CH:13]=[CH:12][N:11]=[CH:10]1)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[Br:14][CH2:15][C:16]1[CH:27]=[CH:26][C:19]([CH:20]=[CH:21][C:22]([O:24][CH3:25])=[O:23])=[CH:18][CH:17]=1>C(#N)C>[Br-:14].[C:1]([N+:9]1[CH:13]=[CH:12][N:11]([CH2:15][C:16]2[CH:17]=[CH:18][C:19]([CH:20]=[CH:21][C:22]([O:24][CH3:25])=[O:23])=[CH:26][CH:27]=2)[CH:10]=1)(=[O:8])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

参加物

4

反応物 2

HCID 663191H-Imidazol-1-ylphenylmethanoneHCID 53395294Methyl 3-(4-(bromomethyl)phenyl)-2-propenoate

生成物 1

HCID 178499872HCID 178499872、化合物収率 83%

試薬・触媒・溶媒 1

HCID 6342Acetonitrile溶媒

実験手順

To 5 ml of dry acetonitrile were added 1.7 g of 1-benzoylimidazole and 2.6 g of methyl 4-bromomethylcinnamate, and the mixture was stirred for 5 hours at room temperature. The precipitated crystals were collected by filtration and recrystallized from acetonitrile/diethyl ether to yield 3.5 g of 1-benzoyl-3-[4-(2-methoxycarbonylvinyl)benzyl]imidazolium bromide.

後処理

  1. filtrationThe precipitated crystals were collected by filtration
  2. customrecrystallized from acetonitrile/diethyl ether

出典と根拠

ORDレコード
ord-e4565a86971646a7be75f1052a5ff618
出典データセット
uspto-grants-1984_09
特許番号
US04469865

関連ノート

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