Sodium Iodide → HCID 13338380、化合物
反応式
[CH3:1][CH:2]1[CH2:4][N:3]1[C:5]1[C:6]2[N:14]([CH3:15])[N:13]=[C:12]([CH3:16])[C:7]=2[N:8]=[C:9]([CH3:11])[N:10]=1.[I-].[Na+]>CC(C)=O>[CH3:15][N:14]1[C:6]2[C:5]3[N:10]([CH2:4][CH:2]([CH3:1])[N:3]=3)[C:9]([CH3:11])=[N:8][C:7]=2[C:12]([CH3:16])=[N:13]1参加物
4
実験手順
The above aziridine (4.4 g, 0.02 mol) in 50 ml of acetone is stirred under reflux with 3.5 g of sodium iodide for three hours and evaporated in vacuo. The residue is partitioned in 150 ml of methylene dichloride and 50 ml of 20% aqueous sodium carbonate solution. The organic layer is separated, dried (MgSO4) and evaporated in vacuo. The resulting solid is recrystallized from acetonitrile to give 2.5 g of the title compound, mp 169°-172° C.
後処理
- customevaporated in vacuo
- customThe residue is partitioned in 150 ml of methylene dichloride
- customThe organic layer is separated
- dry with materialdried (MgSO4)
- customevaporated in vacuo
- customThe resulting solid is recrystallized from acetonitrile
出典と根拠
- ORDレコード
- ord-0dd2833f88254e358151c0255e777577
- 出典データセット
- uspto-grants-1984_09
- 特許番号
- US04469868
反応ノート
読み込み中…