Isopropylamine → 1-Benzyloxy-4-[4-(1-methylethyl)aminobutoxyl]benzene

反応式

[CH2:1]([O:8][C:9]1[CH:14]=[CH:13][C:12]([O:15][CH2:16][CH2:17][CH2:18][CH2:19]Br)=[CH:11][CH:10]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH:21]([NH2:24])([CH3:23])[CH3:22]>>[CH2:1]([O:8][C:9]1[CH:14]=[CH:13][C:12]([O:15][CH2:16][CH2:17][CH2:18][CH2:19][NH:24][CH:21]([CH3:23])[CH3:22])=[CH:11][CH:10]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

参加物

反応物 2

HCID 6363Isopropylamine

HCID 13338479HCID 13338479、化合物

生成物 1

HCID 204469271-Benzyloxy-4-[4-(1-methylethyl)aminobutoxyl]benzene

実験手順

As described in Example 19, 1-benzyloxy-4-(4-bromobutoxy)benzene was reacted with isopropylamine at 100° (12 hours; 500 psi) to give 1-benzyloxy-4-[4-(1-methylethyl)aminobutoxyl]benzene. The crude product was not distilled.

出典と根拠

ORDレコード: ord-5e8cffaea5dd4f8fb04051d5e1125699
出典データセット: uspto-grants-1984_09
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US04471116

反応ノート

読み込み中…