4-(4-methoxyphenyl)-N-(1-methylethyl)butylamine → HCID 20446958、化合物
反応式
C[O:2][C:3]1[CH:8]=[CH:7][C:6]([CH2:9][CH2:10][CH2:11][CH2:12][NH:13][CH:14]([CH3:16])[CH3:15])=[CH:5][CH:4]=1>Br>[CH3:16][CH:14]([NH:13][CH2:12][CH2:11][CH2:10][CH2:9][C:6]1[CH:7]=[CH:8][C:3]([OH:2])=[CH:4][CH:5]=1)[CH3:15]参加物
3
実験手順
4-[4-methoxyphenyl]-N-(1-methylethyl)butylamine (10 g) was added to 48% hydrobromic acid solution (70 ml) and the mixture was refluxed for 3 hours. The residual hydrobromic hydrogen acid was distilled off in vacuo and the residue was made alkaline with 10% sodium carbonate solution. The product was filtered, washed with water and dried to give 5.0 g of 4-[4-(1-methylethyl)aminobutyl]phenol. Mass spectrum and gas chromatography confirmed the identity and purity (93.5%) of the product.
後処理
- temperaturethe mixture was refluxed for 3 hours
- distillationThe residual hydrobromic hydrogen acid was distilled off in vacuo
- filtrationThe product was filtered
- washwashed with water
- customdried
出典と根拠
- ORDレコード
- ord-fa498fab554c422aa8bf4b953a666ce5
- 出典データセット
- uspto-grants-1984_09
- 特許番号
- US04471116
反応ノート
読み込み中…