Dimethylformamide → 3-[(5-Chloro-1,3-benzodithiol-2-ylidene)amino]-2-thioxo-4-thiazolidinone

HRID 2419140ノート

反応式

HRID 2419140 の反応式
[I-].[Cl:2][C:3]1[CH:19]=[CH:18][C:6]2[S:7][C:8](=[N+:10](C)C3C=CC=CC=3)[S:9][C:5]=2[CH:4]=1.C(=O)([O-])[O-].[Na+].[Na+].N[N:27]1[C:31](=[O:32])[CH2:30][S:29][C:28]1=[S:33].CN(C)C=O>O>[Cl:2][C:3]1[CH:19]=[CH:18][C:6]2[S:7][C:8](=[N:10][N:27]3[C:31](=[O:32])[CH2:30][S:29][C:28]3=[S:33])[S:9][C:5]=2[CH:4]=1

参加物

6

反応物 4

HCID 6228DimethylformamideHCID 10340Sodium CarbonateHCID 740333-AminorhodanineHCID 203138445-Chloro-N-methyl-N-phenyl-1,3-benzodithiol-2-iminium iodide

生成物 1

HCID 736760723-[(5-Chloro-1,3-benzodithiol-2-ylidene)amino]-2-thioxo-4-thiazolidinone収率 79%

試薬・触媒・溶媒 1

HCID 962Water溶媒

反応条件

温度
50 °C

実験手順

A mixture of the methiodide of 5-chloro-N-methyl-N-phenyl-1,3-benzodithiol-2-iminium iodide (1.9 g), sodium carbonate (121 mg), N-aminorhodanine (338 mg) and dimethylformamide (20 ml) is heated at 50° C for 3 hours. The mixture is poured into water and the precipitate which forms is filtered and washed with water. The product is recrystallized from dimethylformamide to yield 600 mg of the title compound, melting point 312°-314° C.

後処理

  1. filtrationthe precipitate which forms is filtered
  2. washwashed with water
  3. customThe product is recrystallized from dimethylformamide

出典と根拠

ORDレコード
ord-e3e871ef7ecb4fb68e413882d542ce55
出典データセット
uspto-grants-1978_08
特許番号
US04104467

反応ノート

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