Sodium Hydroxide → Clazolimine
反応式
[OH-:1].[Na+].[Cl:3][C:4]1[CH:9]=[CH:8][C:7]([NH:10][C:11]#[N:12])=[CH:6][CH:5]=1.[CH3:13][NH:14][C:15](=O)[CH2:16]Cl>O>[Cl:3][C:4]1[CH:9]=[CH:8][C:7]([N:10]2[CH2:16][C:15](=[O:1])[N:14]([CH3:13])[C:11]2=[NH:12])=[CH:6][CH:5]=1参加物
5
実験手順
In 25 ml. of water containing 0.84 g. of sodium hydroxide was dissolved in 3.2 g. of p-chlorophenylcyanamide. To the clear solution was added 2.25 g. of N-methylchloroacetamide. The reaction mixture was stirred for 48 hours at room temperature. The precipitate was filtered to yield 1.9 g. of product, m.p. 182°-184° C. After the initial product was filtered, the filtrate was left stirring another three days. An additional 1.2 g. of product precipitated from solution. Total yield of product was 3.1 g. (66%).
後処理
- additionTo the clear solution was added 2.25 g
- filtrationThe precipitate was filtered
- customto yield 1.9 g
- filtrationAfter the initial product was filtered
- waitthe filtrate was left
- stirringstirring another three days
- customof product precipitated from solution
出典と根拠
- ORDレコード
- ord-5fa5e1d65f7c4b00bf98fc3955064a78
- 出典データセット
- uspto-grants-1978_08
- 特許番号
- US04110445
反応ノート
読み込み中…