O-Methylhydroxylamine → N-methoxy-3-(2-chloro-4-iodo-phenylamino)-isonicotinamide
反応式
[Cl:1][C:2]1[CH:7]=[C:6]([I:8])[CH:5]=[CH:4][C:3]=1[NH:9][C:10]1[CH:18]=[N:17][CH:16]=[CH:15][C:11]=1[C:12](O)=[O:13].[CH3:19][O:20][NH2:21]>>[CH3:19][O:20][NH:21][C:12](=[O:13])[C:11]1[CH:15]=[CH:16][N:17]=[CH:18][C:10]=1[NH:9][C:3]1[CH:4]=[CH:5][C:6]([I:8])=[CH:7][C:2]=1[Cl:1]参加物
3
実験手順
N-methoxy-3-(2-chloro-4-iodo-phenylamino)-isonicotinamide was synthesized according to the procedure for General Method 1, outlined above, starting with 0.30 mmol of 3-[(2-chloro-4-iodophenyl)amino]isonicotinic acid (intermediate 2) and 0.42 mmol of O-methyl-hydroxylamine. LC/MS [8.75 min; 404 (M+1)]
後処理
- customLC/MS [8.75 min; 404 (M+1)]
出典と根拠
- ORDレコード
- ord-db4b470d42a643e09fe7c7bc3e41dd8d
- 出典データセット
- uspto-grants-2011_06
- 特許番号
- US07956191B2
反応ノート
読み込み中…