1,2-Dichloroethane → HCID 86628743、化合物

反応式

OC[CH2:3][C:4](C)([S:6][C:7]1[CH:15]=[CH:14][C:10]([C:11](O)=[O:12])=[CH:9][C:8]=1[N+:16]([O-:18])=[O:17])[CH3:5].S(Cl)([Cl:22])=O.Cl[CH2:25][CH2:26][Cl:27]>>[Cl:27][CH2:26][CH2:25][C:4]([CH3:5])([S:6][C:7]1[CH:15]=[CH:14][C:10]([C:11]([Cl:22])=[O:12])=[CH:9][C:8]=1[N+:16]([O-:18])=[O:17])[CH3:3]

参加物

反応物 3

HCID 111,2-Dichloroethane

HCID 24386Thionyl Chloride

HCID 672422364-(4-Hydroxy-2-methylbutan-2-ylthio)-3-nitrobenzoic acid

生成物 1

HCID 86628743HCID 86628743、化合物

反応条件

温度: 70 °C

実験手順

To a solution of 4-(4-hydroxy-2-methylbutan-2-ylthio)-3-nitrobenzoic acid (3.08 g, 10.8 mmol) in DCE (50 mL) was added thionyl chloride (2.365 mL, 32.4 mmol). The reaction was heated to 70° C. and stirred at that temperature for 1 hour. The solvent was removed under reduced pressure and the resulting oil was used without further purification.