Thionyl Chloride → 2-Chloro-2-oxoethyl 4'-chlorobiphenyl-4-sulfonate

HRID 2422925

反応式

HRID 2422925 の反応式
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:13]=[CH:12][C:11]([S:14]([O:17][CH2:18][C:19]([OH:21])=O)(=[O:16])=[O:15])=[CH:10][CH:9]=2)=[CH:4][CH:3]=1.S(Cl)([Cl:24])=O>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:13]=[CH:12][C:11]([S:14]([O:17][CH2:18][C:19]([Cl:24])=[O:21])(=[O:16])=[O:15])=[CH:10][CH:9]=2)=[CH:4][CH:3]=1

参加物

3

反応物 2

HCID 24386Thionyl ChlorideHCID 86628700HCID 86628700、化合物

生成物 1

HCID 866287022-Chloro-2-oxoethyl 4'-chlorobiphenyl-4-sulfonate

実験手順

A mixture of acid 13 (100 mg, 0.306 mmol) and thionyl chloride (1 ml) was heated at reflux for 1.5 h. The excess thionyl chloride was removed in vacuo and the resulting pale yellow/white solid dried under high vacuum at 50° C. for 1.5 h. The product acid chloride 14 was used without further purification.

後処理

  1. temperaturewas heated
  2. temperatureat reflux for 1.5 h
  3. customThe excess thionyl chloride was removed in vacuo
  4. customthe resulting pale yellow/white solid dried under high vacuum at 50° C. for 1.5 h
  5. customThe product acid chloride 14 was used without further purification

出典と根拠

ORDレコード
ord-d8e1d267abee4aeba70658dc436a7c38
出典データセット
uspto-grants-2011_06
特許番号
US07960434B2

関連ノート

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