Ethyl bromoacetate → (4-Acetyl-2-ethyl-3-hydroxy-phenoxy)-acetic acid ethyl ester
反応式
[CH2:1]([C:3]1[C:4]([OH:13])=[C:5]([C:10](=[O:12])[CH3:11])[CH:6]=[CH:7][C:8]=1[OH:9])[CH3:2].[CH2:14]([O:16][C:17](=[O:20])[CH2:18]Br)[CH3:15]>>[CH2:14]([O:16][C:17](=[O:20])[CH2:18][O:9][C:8]1[CH:7]=[CH:6][C:5]([C:10](=[O:12])[CH3:11])=[C:4]([OH:13])[C:3]=1[CH2:1][CH3:2])[CH3:15]参加物
3
実験手順
1-(3-Ethyl-2,4-dihydroxy-phenyl)-ethanone was treated with 2-bromo-acetic acid ethyl ester and processed as described in the synthesis of example 20a. Yield, 96.89%; mp, 74-75° C.; MS (CI): 267 (M++1).
後処理
- customas described in the synthesis of example 20a
- customYield
- custommp, 74-75° C.
出典と根拠
- ORDレコード
- ord-256836ddf67c4667953ad9803e137f18
- 出典データセット
- uspto-grants-2011_06
- 特許番号
- US07964628B2
反応ノート
読み込み中…