Dimethylamine → 2-(1,4-diazepan-1-yl)-N,N-dimethylacetamide dihydrochloride

反応式

C(O[C:6]([N:8]1[CH2:14][CH2:13][CH2:12][NH:11][CH2:10][CH2:9]1)=O)(C)(C)C.[Cl:15]C[C:17](Cl)=[O:18].[CH3:20][NH:21][CH3:22]>>[ClH:15].[ClH:15].[N:8]1([CH2:6][C:17]([N:21]([CH3:22])[CH3:20])=[O:18])[CH2:14][CH2:13][CH2:12][NH:11][CH2:10][CH2:9]1

参加物

反応物 3

HCID 674Dimethylamine

HCID 6577Chloroacetyl chloride

HCID 2756058Tert-butyl 1,4-diazepane-1-carboxylate

生成物 1

HCID 672461842-(1,4-diazepan-1-yl)-N,N-dimethylacetamide dihydrochloride

実験手順

prepared from [1,4]diazepane-1-carboxylic acid tert-butyl ester, chloroacetylchloride and dimethylamine in an analogous manner as described in example 15.

出典と根拠

ORDレコード: ord-c7b48af1e19548199d9d0d53f2fa2670
出典データセット: uspto-grants-2011_06
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US07964724B2

反応ノート

読み込み中…