5-Fluoroisatin → 5-fluoro-1,3-dihydro-2H-indol-2-one
反応式
[F:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][C:6](=[O:11])[C:5]2=O>O.NN>[F:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][C:6](=[O:11])[CH2:5]2参加物
3
実験手順
5-Fluoroisatin (8.2 g) was dissolved in 50 mL of hydrazine hydrate and refluxed for 1.0 hr. The reaction mixtures were then poured in ice water. The precipitate was then filtered, washed with water and dried in a vacuum oven to afford the title compound.
後処理
- temperaturerefluxed for 1.0 hr
- customThe reaction mixtures
- filtrationThe precipitate was then filtered
- washwashed with water
- customdried in a vacuum oven
出典と根拠
- ORDレコード
- ord-85f8d0a13c1741908216e141c66ffd9d
- 出典データセット
- uspto-grants-2005_02
- 特許番号
- US06855730B2
反応ノート
読み込み中…