関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Acetone Cyanohydrin | HCID 6406 | — |
| 反応物 | p-Toluidine | HCID 7813 | — |
| 生成物 | 2-Methyl-2-[(4-methylphenyl)amino]propanenitrile | HCID 21239243 | 99% |
反応手順
A mixture of p-toluidine (1.07 g, 10 mmol) and acetone cyanohydrin (10 ml) was heated to 80° C. and stirred for 4 h. The medium was concentrated and dried under vacuum to yield 2-methyl-2-(4-methylphenyl)aminopropanenitrile, 5a (1.72 g, 9.9 mmol, 99%) as brown solid.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US08658681B2 |
|---|
| 出典データセット | uspto-grants-2014_02 |
|---|
| ORD ID | ord-2c9e85e79b0847ab9dc519139d06e06d |
|---|
| 出典メモ | uspto-grants-2014_02 |
|---|
