(3-Bromophenyl)acetic acid → Ethyl 3-(bromophenyl)acetate

反応式

Br[C:2]1[CH:7]=[CH:6][C:5]([CH2:8][C:9]([O:11][CH2:12][CH3:13])=[O:10])=[CH:4][CH:3]=1.[Br:14]C1C=C(CC(O)=O)C=CC=1>>[Br:14][C:3]1[CH:4]=[C:5]([CH2:8][C:9]([O:11][CH2:12][CH3:13])=[O:10])[CH:6]=[CH:7][CH:2]=1

参加物

反応物 2

HCID 74653(3-Bromophenyl)acetic acid

HCID 7020609Ethyl 2-(4-bromophenyl)acetate2 回

生成物 1

HCID 11470552Ethyl 3-(bromophenyl)acetate

実験手順

Employing the same general procedure as for the preparation of ethyl (4-bromophenyl)acetate (Compound A), 100 g (463 mmol) of 3-bromophenylacetic acid was converted into the title compound (yellow oil) using 2 g of conc. H2SO4 and 500 ml of ethanol.

出典と根拠

ORDレコード: ord-13b89fea485a4edfacf2184795d38ef0
出典データセット: uspto-grants-2005_02
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US06855832B2

反応ノート

読み込み中…