Methyl iodide → HCID 20162056、化合物
反応式
[C:1](=O)([O-])[O-].[K+].[K+].CI.[Cl:9][C:10]1([C:15]([OH:17])=[O:16])[CH2:12][C:11]1([Cl:14])[Cl:13]>CN(C)C(=O)C>[Cl:9][C:10]1([C:15]([O:17][CH3:1])=[O:16])[CH2:12][C:11]1([Cl:14])[Cl:13]参加物
5
実験手順
Potassium carbonate (4.14 grams) and methyl iodide (3.74 ml) were added to a solution of 1,2,2-trichlorocyclopropane carboxylic acid (5.68 grams) and N,N-dimethylacetamide (50 ml). The reaction mixture was stirred for approximately 20 hours and then filtered. Ethyl ether (250 ml) was added to the filtrate and the resultant mixture was washed, dried, and evaporated in vacuo to the desired product, methyl 1,2,2-trichlorocyclopropane carboxylate. Structure of the product was confirmed by NMR.
後処理
- filtrationfiltered
- additionEthyl ether (250 ml) was added to the filtrate
- washthe resultant mixture was washed
- customdried
- customevaporated in vacuo to the desired product, methyl 1,2,2-trichlorocyclopropane carboxylate
出典と根拠
- ORDレコード
- ord-42f238a7495542028547310e3b96da5e
- 出典データセット
- uspto-grants-1987_11
- 特許番号
- US04704156
反応ノート
読み込み中…