反応式
[C:1]([O:5][C:6](=[O:9])[CH:7]=[CH2:8])(=[O:4])[CH:2]=[CH2:3].NCCC1C=CN=CC=1>>[C:1]([O:5][C:6](=[O:9])[CH:7]=[CH2:8])(=[O:4])[CH:2]=[CH2:3].[C:1]([OH:5])(=[O:4])[CH:2]=[CH2:3].[C:1]([O:5][C:6](=[O:9])[CH3:7])(=[O:4])[CH3:2]参加物
実験手順
This substituted acrylamide was synthesized from acrylic anhydride and 4-(2-aminoethyl)pyridine. Acrylic anhydride was obtained from acrylic acid and acetic anhydride. Synthesis of PEAM was initiated by the slow addition of 0.36 mole (45.0 g) of acrylic anhydride in 50 ml of ethyl ether containing 50 mg of BHT to 0.35 mole (42.76 g) of 4-(2-aminoethyl)pyridine in 150 ml of ethyl ether containing 150 mg of BHT at -55° C., with the formation of a precipitate. The rate of addition was kept sufficiently slow to ensure that the temperature did not exceed -30° C. during the reaction. After removal of the ether by room temperature evaporation, the precipitate was dissolved in 200 ml of methanol and subsequently vacuum distilled. The substituted acrylamide (15% yield) was collected at 170° C., 100 mtorr.
出典と根拠
- ORDレコード
- ord-e71a7cfbfb834ca2af1ad56ad144ca1f
- 出典データセット
- uspto-grants-1987_11
- 特許番号
- US04705753
関連ノート
読み込み中…