Sodium Hydroxide → HCID 178443036、化合物

HRID 247157

反応式

HRID 247157 の反応式
[OH-].[CH2:2]([N+:18]([CH3:21])([CH3:20])[CH3:19])[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH3:17].[CH2:22]([O:24][C:25]1[CH:33]=[CH:32][C:28]([C:29]([OH:31])=[O:30])=[C:27]([OH:34])[CH:26]=1)[CH3:23].[OH-].[Na+]>>[CH2:22]([O:24][C:25]1[CH:26]=[C:27]([OH:34])[C:28](=[CH:32][CH:33]=1)[C:29]([O-:31])=[O:30])[CH3:23].[CH2:2]([N+:18]([CH3:21])([CH3:19])[CH3:20])[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH3:17]

参加物

4

反応物 3

HCID 14798Sodium HydroxideHCID 68166Cetrimonium HydroxideHCID 826284-Ethoxysalicylic acid

生成物 1

HCID 178443036HCID 178443036、化合物

実験手順

The last third of the cetyl-trimethylammonium hydroxide solution is neutralized with 12.39 g of 4-ethoxy-2-hydroxy-benzoic acid (the equivalent weight of which has been determined as 185.8 by titration with 0.1N sodium hydroxide solution) by scattering in as a powder. The resulting yellow solution in methanol is concentrated to dryness. 31.1 g of a slightly brownish residue are obtained, which can be purified by recrystallization from 300 ml of ethyl acetate several times. Cetyl-trimethylammonium 4-ethoxysalicylate is obtained in (slightly reddish) crystals (titration with perchloric acid in glacial acetic acid gives the expected equivalent weight).

後処理

  1. concentrationThe resulting yellow solution in methanol is concentrated to dryness
  2. custom31.1 g of a slightly brownish residue are obtained
  3. customwhich can be purified by recrystallization from 300 ml of ethyl acetate several times

出典と根拠

ORDレコード
ord-f521c99de5604056aadd43cae97847b6
出典データセット
uspto-grants-1987_11
特許番号
US04705860

関連ノート

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