Ethanol → 3-(1-Ethoxy-1-phenyl-methylidene)-2-indolinone

HRID 24740ノート

反応式

HRID 24740 の反応式
C([N:4]1[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[C:6](=[C:13]([O:20][CH2:21][CH3:22])[C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[C:5]1=[O:23])(=O)C.C(O)C.[OH-].[Na+]>O>[CH2:21]([O:20][C:13](=[C:6]1[C:7]2[C:12](=[CH:11][CH:10]=[CH:9][CH:8]=2)[NH:4][C:5]1=[O:23])[C:14]1[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=1)[CH3:22]

参加物

5

反応物 3

HCID 702EthanolHCID 14798Sodium HydroxideHCID 542378881-Acetyl-3-(1-ethoxy-1-phenylmethylidene}-2-indolinone

生成物 1

HCID 540376233-(1-Ethoxy-1-phenyl-methylidene)-2-indolinone

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

6.15 g (20 mmol) of 1-acetyl-3-(1-ethoxy-1-phenyl-methylidene)-2-indolinone are suspended in a little ethanol. 10 ml of 4N sodium hydroxide solution are added and the mixture is stirred for 1.5 hours at ambient temperature. After the addition of 100 ml of water the precipitate is suction filtered, washed with water and a little ether and dried at 80° C.

後処理

  1. filtrationfiltered
  2. washwashed with water
  3. dry with materiala little ether and dried at 80° C.

出典と根拠

ORDレコード
ord-2873a7ec518c40c286dc86ec59daace2
出典データセット
uspto-grants-2005_02
特許番号
US06855710B2

反応ノート

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