Sodium Hydroxide → 3-(1-Ethoxy-1-phenyl-methylidene)-2-indolinone

HRID 24767ノート

反応式

HRID 24767 の反応式
C([N:4]1[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[C:6](=[C:13]([O:20][CH2:21][CH3:22])[C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[C:5]1=[O:23])(=O)C.[OH-].[Na+]>C(O)C.O>[CH2:21]([O:20][C:13](=[C:6]1[C:7]2[C:12](=[CH:11][CH:10]=[CH:9][CH:8]=2)[NH:4][C:5]1=[O:23])[C:14]1[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=1)[CH3:22]

参加物

5

反応物 2

HCID 14798Sodium HydroxideHCID 542378881-Acetyl-3-(1-ethoxy-1-phenylmethylidene}-2-indolinone

生成物 1

HCID 540376233-(1-Ethoxy-1-phenyl-methylidene)-2-indolinone

試薬・触媒・溶媒 2

HCID 702Ethanol溶媒HCID 962Water溶媒

実験手順

4.0 g (13.2 mmol) of 1-acetyl-3-(1-ethoxy-1-phenyl-methylidene)-2-indolinone are suspended in 50 ml of ethanol and after the addition of 10 ml of 4N sodium hydroxide solution stirred for 90 minutes at ambient temperature. The solution is diluted with 150 ml of water, the crystalline product is suction filtered, washed and dried.

後処理

  1. filtrationfiltered
  2. washwashed
  3. customdried

出典と根拠

ORDレコード
ord-18b3187e488642c0a3b625cd6c1e19ec
出典データセット
uspto-grants-2005_02
特許番号
US06855710B2

反応ノート

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