Hydrochloric Acid → 3-Phenoxybenzyl alcohol

HRID 247725

反応式

HRID 247725 の反応式
C([O:4][CH2:5][C:6]1[CH:11]=[CH:10][CH:9]=[C:8]([O:12][C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)[CH:7]=1)(=O)C.Cl>CO>[O:12]([C:8]1[CH:7]=[C:6]([CH:11]=[CH:10][CH:9]=1)[CH2:5][OH:4])[C:13]1[CH:14]=[CH:15][CH:16]=[CH:17][CH:18]=1

参加物

4

反応物 2

HCID 313Hydrochloric AcidHCID 170904Benzenemethanol, 3-phenoxy-, 1-acetate

生成物 1

HCID 262953-Phenoxybenzyl alcohol収率 90%

試薬・触媒・溶媒 1

HCID 887Methanol溶媒

実験手順

2.42 g. (0.01 mole) of 3-phenoxybenzyl acetate, 5 cm3. of methanol and 5 cm3. of 2N hydrochloric acid solution are refluxed for three hours. Then the methanol is distilled off. The organic phase is dissolved in 30 cm3. of methylene chloride, washed with 10 cm3. of water, 10 cm3. of 1N sodium hydroxide solution and 10 cm3. of water then evaporated. 1.8 g. of 3-phenoxybenzyl alcohol are obtained. nD20 : 1.593, yield 90%.

後処理

  1. distillationThen the methanol is distilled off
  2. dissolutionThe organic phase is dissolved in 30 cm3
  3. washof methylene chloride, washed with 10 cm3
  4. customof water then evaporated

出典と根拠

ORDレコード
ord-f90801a985d04be688f6c4e70178ce4b
出典データセット
uspto-grants-1987_11
特許番号
US04709081

関連ノート

読み込み中…