1,1,1-Trifluoro-2-decyl 4-hydroxybenzoate → Benzoic acid, 4-((1-oxodecyl)oxy)-

HRID 247788

反応式

[C:1]([O:12][C:13]1[CH:41]=[CH:40][C:16]([C:17]([O:19][C:20]2[CH:25]=[CH:24][C:23]([C:26]([O:28][CH:29]([CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH3:39])[C:30]([F:33])([F:32])[F:31])=[O:27])=[CH:22][CH:21]=2)=[O:18])=[CH:15][CH:14]=1)(=[O:11])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10].OC1C=CC(C(OC(CCCCCCCC)C(F)(F)F)=O)=CC=1>O1CCCC1>[C:1]([O:12][C:13]1[CH:41]=[CH:40][C:16]([C:17]([OH:19])=[O:18])=[CH:15][CH:14]=1)(=[O:11])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10].[C:1]([O:12][C:13]1[CH:41]=[CH:40][C:16]([C:17]([O:19][C:20]2[CH:21]=[CH:22][C:23]([C:26]([O:28][CH:29]([CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH3:39])[C:30]([F:33])([F:32])[F:31])=[O:27])=[CH:24][CH:25]=2)=[O:18])=[CH:15][CH:14]=1)(=[O:11])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10]

参加物

実験手順

To a solution of the 4-n-decanoyloxybenzoic acid (0.43 g) obtained in Example 12, (3) and the 1,1,1-trifluoro-2-octyl 4-hydroxybenzoate (0.4 g) obtained in (2) above in tetrahydrofuran (about 30 ml) were added dicyclohexylcarbodiimide (0.32 g) and dimethylamonopyridine (0.01 g). The mixture was stirred at room temperature for about 20 hours and was distilled to remove the solvent. The residue was dissolved in dichloromethane and washed with water. The organic layer was dried over anhydrous magnesium sulfate and was distilled to remove the solvent. The residue was purified by silica-gel column chromatography (developer : hexane/ ethyl acetate=20/1) to obtain the titled compound (0.20 g).

出典と根拠

ORDレコード: ord-76d2acb9c9be47e299d7228a7db3f18a
出典データセット: uspto-grants-1993_05
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US05207947

反応式

参加物

反応物 2

生成物 2

試薬・触媒・溶媒 1

実験手順

出典と根拠

関連ノート