化工社化工社 化学情報印刷レポート · 研究参考用
Methylparaben → Methyl 4-(tetradecyloxy)benzoate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Methylparaben | HCID 7456 | — |
| 反応物 | Myristyl bromide | HCID 8208 | — |
| 反応物 | Potassium Carbonate | HCID 11430 | — |
| 溶媒 | Methyl Ethyl Ketone | HCID 6569 | — |
| 生成物 | Methyl 4-(tetradecyloxy)benzoate | HCID 3312490 | — |
反応手順
A mixture of 150 g methyl-4-hydroxybenzoate, 1.5 L 2-butanone, 272.5 g potassium carbonate and 293 ml 1-bromotetradecane is heated at reflux for 66 hours. The reaction is cooled to room temperature, filtered, the filtrate concentrated in vacuo and the residue recrystallized from methylene chloride/hexane to give 258.8 g of the desired product. MP 56°-58° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05208247 |
| 出典データセット | uspto-grants-1993_05 |
| ORD ID | ord-6b25509aea6d47dfb14ef8b085b63220 |
| 出典メモ | uspto-grants-1993_05 |