反应详情

A mixture of 150 g methyl-4-hydroxybenzoate, 1.5 L 2-butanone, 272.5 g potassium carbonate and 293 ml 1-bromotetradecane is heated at reflux for 66 hours. The reaction is cooled to room temperature, filtered, the filtrate concentrated in vacuo and the residue recrystallized from methylene chloride/hexane to give 258.8 g of the desired product. MP 56°-58° C.

1. temperatureis heated
2. temperatureat reflux for 66 hours
3. filtrationfiltered
4. concentrationthe filtrate concentrated in vacuo
5. customthe residue recrystallized from methylene chloride/hexane