Oxalyl chloride → Benzoyl chloride, 4-(tetradecyloxy)-

HRID 247913

反応式

HRID 247913 の反応式
[CH2:1]([O:15][C:16]1[CH:24]=[CH:23][C:19]([C:20](O)=[O:21])=[CH:18][CH:17]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH3:14].C(Cl)(=O)C([Cl:28])=O>CN(C)C=O.C(Cl)Cl>[CH2:1]([O:15][C:16]1[CH:24]=[CH:23][C:19]([C:20]([Cl:28])=[O:21])=[CH:18][CH:17]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH3:14]

参加物

5

反応物 2

HCID 65578Oxalyl chlorideHCID 2894104-(Tetradecyloxy)benzoic acid

生成物 1

HCID 9998158Benzoyl chloride, 4-(tetradecyloxy)-

試薬・触媒・溶媒 2

HCID 6228Dimethylformamide触媒HCID 6344Dichloromethane溶媒

実験手順

To a room temperature suspension of 15 g of product from Example 2, 160 ml methylene chloride and 5 drops dimethylformamide is added 5.87 ml oxalyl chloride. The reaction mixture is stirred at room temperature for 18 hours, concentrated in vacuo, dissolved in 300 ml of diethyl ether, filtered through diatomaceous earth and the filtrate concentrated in vacuo to give 15.5 g of the desired product.

後処理

  1. concentrationconcentrated in vacuo
  2. dissolutiondissolved in 300 ml of diethyl ether
  3. filtrationfiltered through diatomaceous earth
  4. concentrationthe filtrate concentrated in vacuo

出典と根拠

ORDレコード
ord-724eb1a2d07c4cb6a7e2a01dabb3dd33
出典データセット
uspto-grants-1993_05
特許番号
US05208247

関連ノート

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