関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Iodoethane | HCID 6340 | — |
| 反応物 | N-(2-Pyridinylmethyl)-4-(tetradecyloxy)benzamide | HCID 10093859 | — |
| 生成物 | 1-Ethyl-2-[[[4-(tetradecyloxy)benzoyl]amino]methyl]pyridinium iodide | HCID 19016226 | — |
反応手順
A mixture of 1.0 g of product from Example 4 and 9.42 ml of ethyl iodide is heated, in a sealed dark tube, at 140° C. for 20 hours. The cooled reaction mixture is concentrated in vacuo, the residue purified by column chromatography (silica gel:10% methyl alcohol/chloroform) and recrystallized from 5% chloroform/methyl alcohol to give 0.96 g of the desired product.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US05208247 |
|---|
| 出典データセット | uspto-grants-1993_05 |
|---|
| ORD ID | ord-58e62dd22d0241b4a70948708cab22d3 |
|---|
| 出典メモ | uspto-grants-1993_05 |
|---|
