Methyl iodide → 2-[[Acetyl[3,4-bis(heptyloxy)benzoyl]amino]methyl]-1-methylpyridinium iodide
反応式
[C:1]([N:4]([CH2:29][C:30]1[CH:35]=[CH:34][CH:33]=[CH:32][N:31]=1)[C:5](=[O:28])[C:6]1[CH:11]=[CH:10][C:9]([O:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH3:19])=[C:8]([O:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH3:27])[CH:7]=1)(=[O:3])[CH3:2].[CH3:36][I:37]>>[I-:37].[C:1]([N:4]([CH2:29][C:30]1[CH:35]=[CH:34][CH:33]=[CH:32][N+:31]=1[CH3:36])[C:5](=[O:28])[C:6]1[CH:11]=[CH:10][C:9]([O:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH3:19])=[C:8]([O:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH3:27])[CH:7]=1)(=[O:3])[CH3:2]参加物
3
反応条件
- 温度
- 105 °C
実験手順
A mixture of 1.0 g of product from Example 112 and 14.7 g of methyl iodide is heated in a sealed tube at 105° C. from 171/4 hours. The reaction is concentrated in vacuo to give 1.24 g of the desired product as yellow crystals.
後処理
- concentrationThe reaction is concentrated in vacuo