Oxalyl chloride → 4-(Decyloxy)-3-(1,1-dimethylethyl)benzoyl chloride

HRID 248029ノート

反応式

HRID 248029 の反応式
[CH2:1]([O:11][C:12]1[CH:20]=[CH:19][C:15]([C:16](O)=[O:17])=[CH:14][C:13]=1[C:21]([CH3:24])([CH3:23])[CH3:22])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10].C(Cl)(=O)C([Cl:28])=O>C(Cl)Cl.CN(C)C=O>[CH2:1]([O:11][C:12]1[CH:20]=[CH:19][C:15]([C:16]([Cl:28])=[O:17])=[CH:14][C:13]=1[C:21]([CH3:24])([CH3:23])[CH3:22])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10]

参加物

5

反応物 2

HCID 65578Oxalyl chlorideHCID 19015379HCID 19015379、化合物

生成物 1

HCID 190152784-(Decyloxy)-3-(1,1-dimethylethyl)benzoyl chloride

試薬・触媒・溶媒 2

HCID 6228Dimethylformamide触媒HCID 6344Dichloromethane溶媒

実験手順

To 3.0 g of product from Example 131 in 30 ml of methylene chloride plus 2 drops of dimethylformamide is added 2.0 ml of oxalyl chloride via syringe. The reaction is stirred at room temperature for 18 hours, concentrated in vacuo, dissolved in diethyl ether and filtered through a pad of diatomaceous earth. The diethyl ether is concentrated in vacuo to give 3.15 g of the desired product as a yellow oil.

後処理

  1. concentrationconcentrated in vacuo
  2. dissolutiondissolved in diethyl ether
  3. filtrationfiltered through a pad of diatomaceous earth
  4. concentrationThe diethyl ether is concentrated in vacuo

出典と根拠

ORDレコード
ord-e65ced7b3fc7456695c8474d51e385c2
出典データセット
uspto-grants-1993_05
特許番号
US05208247

反応ノート

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