Sodium Iodide → Isopropoxycarbonyloxyethyl iodide
反応式
[CH:1]([O:4][C:5]([O:7][CH2:8][CH2:9]Cl)=[O:6])([CH3:3])[CH3:2].[I-:11].[Na+]>[Cl-].[Zn+2].[Cl-].C(Cl)(Cl)(Cl)Cl>[CH:1]([O:4][C:5]([O:7][CH2:8][CH2:9][I:11])=[O:6])([CH3:3])[CH3:2]参加物
5
実験手順
A mixture of isopropoxycarbonyloxyethyl chloride (=2-chloroethyl isopropylcarbonate) (1.67 g), carbon tetrachloride (10 ml), sodium iodide (2.10 g) and anhydrous zinc chloride (0.08 g) is stirred at room temperature for 2 hours, and thereafter, ice water is added to the mixture. The organic layer is separated, and the aqueous layer is extracted twice.with carbon tetrachloride. The combined organic layers are washed, dried and evaporated under reduced pressure to give isopropoxycarbonyloxyethyl iodide (=2-iodoethyl isopropylcarbonate) (1.48 g) as an oil.
後処理
- customThe organic layer is separated
- extractionthe aqueous layer is extracted twice.with carbon tetrachloride
- washThe combined organic layers are washed
- customdried
- customevaporated under reduced pressure
出典と根拠
- ORDレコード
- ord-89e5832df91a4a02a5a9d6bf1742368b
- 出典データセット
- uspto-grants-1993_05
- 特許番号
- US05208348
反応ノート
読み込み中…