Sodium Hydroxide → HCID 178453075、化合物

HRID 24828

反応式

HRID 24828 の反応式
C([N:4]1[C:12]2[C:7](=[CH:8][C:9]([N+:13]([O-:15])=[O:14])=[CH:10][CH:11]=2)[C:6](=[C:16](OCC)[C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)[C:5]1=[O:26])(=O)C.[C:27]([O:31][C:32]([NH:34][CH2:35][C:36]1[CH:42]=[CH:41][C:39]([NH2:40])=[CH:38][CH:37]=1)=[O:33])([CH3:30])([CH3:29])[CH3:28].[OH-].[Na+]>CN(C=O)C.CO>[C:27]([O:31][C:32]([NH:34][CH2:35][C:36]1[CH:42]=[CH:41][C:39]([NH:40]/[C:16](=[C:6]2\[C:5](=[O:26])[NH:4][C:12]3[C:7]\2=[CH:8][C:9]([N+:13]([O-:15])=[O:14])=[CH:10][CH:11]=3)/[C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)=[CH:38][CH:37]=1)=[O:33])([CH3:30])([CH3:28])[CH3:29]

参加物

6

反応物 3

HCID 14798Sodium HydroxideHCID 2756041tert-butyl N-[(4-aminophenyl)methyl]carbamateHCID 542801041-Acetyl-3-{1-ethoxy-1-phenylmethylidene}-5-nitro-2-indolinone

生成物 1

HCID 178453075HCID 178453075、化合物

試薬・触媒・溶媒 2

HCID 887Methanol溶媒HCID 6228Dimethylformamide溶媒

実験手順

Prepared analogously to Example 82 from 1-acetyl-3-(1-ethoxy-1-phenyl-methylidene)-5-nitro-2-indolinone and 4-tert.butoxycarbonylaminomethyl-aniline in DMF and subsequent treatment with sodium hydroxide solution in methanol.

出典と根拠

ORDレコード
ord-cbfbc54cff7e4c43a14266785e577960
出典データセット
uspto-grants-2005_02
特許番号
US06855710B2

関連ノート

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