関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | (Diethylamino)sulfur trifluoride | HCID 123472 | — |
| 反応物 | (Trifluoromethyl)trimethylsilane | HCID 552549 | — |
| 反応物 | Tetrabutylammonium Fluoride | HCID 2724141 | — |
| 反応物 | HCID 178447904 | HCID 178447904 | — |
| 溶媒 | Tetrahydrofuran | HCID 8028 | — |
| 生成物 | HCID 178447877 | HCID 178447877 | — |
反応手順
A mixture of 10 mmol of 4-(trans-4-propylcyclohexyl)cyclohexanone, 11 mmol of trimethyl(trifluoromethyl)silane, 10 mmol of tetrabutylammonium fluoride and 50 ml of THF is stirred for 2 hours at 0° C. After customary work-up, the crude product is dissolved in 20 mml of THF, 10 mmol of DAST are added, and the mixture is heated to boiling. After customary work-up, the crude product is purified by chromatography and crystallization.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US05209868 |
|---|
| 出典データセット | uspto-grants-1993_05 |
|---|
| ORD ID | ord-93000c1993c1467d8c958cf156ab0696 |
|---|
| 出典メモ | uspto-grants-1993_05 |
|---|
