反应详情

温度

0 °C

A mixture of 10 mmol of 4-(trans-4-propylcyclohexyl)cyclohexanone, 11 mmol of trimethyl(trifluoromethyl)silane, 10 mmol of tetrabutylammonium fluoride and 50 ml of THF is stirred for 2 hours at 0° C. After customary work-up, the crude product is dissolved in 20 mml of THF, 10 mmol of DAST are added, and the mixture is heated to boiling. After customary work-up, the crude product is purified by chromatography and crystallization.

1. additionare added
2. temperaturethe mixture is heated to boiling
3. customAfter customary work-up, the crude product is purified by chromatography and crystallization