2-(N-Benzyl-N-methylamino)-1-(N-piperidinyl)ethane → Methyl(2-(piperidin-1-yl)ethyl)amine
反応式
[CH2:1]([N:8]([CH2:10][CH2:11][N:12]1[CH2:17][CH2:16][CH2:15][CH2:14][CH2:13]1)C)C1C=CC=CC=1>CCO.[OH-].[OH-].[Pd+2]>[CH3:1][NH:8][CH2:10][CH2:11][N:12]1[CH2:17][CH2:16][CH2:15][CH2:14][CH2:13]1参加物
4
実験手順
A solution of the title compound of Step 11 (1.85 g, 7.96mmol) and 20% Pd(OH)2 on carbon in EtOH (50 mL) was placed under a hydrogen atmosphere (60 psi) at room temperature for 17 hours. The mixture was filtered and concentrated to give the title compound as a clear, yellow liquid (1.02 g, 90% crude yield). The proton spectral data were consistent with the proposed structure.
後処理
- customat room temperature
- customfor 17 hours
- filtrationThe mixture was filtered
- concentrationconcentrated
出典と根拠
- ORDレコード
- ord-24f9471b682b46ea902a3d42b6b01974
- 出典データセット
- uspto-grants-1993_05
- 特許番号
- US05212185
反応ノート
読み込み中…