2-(N-Benzyl-N-methylamino)-1-(N-piperidinyl)ethane → Methyl(2-(piperidin-1-yl)ethyl)amine

HRID 248874

反応式

HRID 248874 の反応式
[CH2:1]([N:8]([CH2:10][CH2:11][N:12]1[CH2:17][CH2:16][CH2:15][CH2:14][CH2:13]1)C)C1C=CC=CC=1>CCO.[OH-].[OH-].[Pd+2]>[CH3:1][NH:8][CH2:10][CH2:11][N:12]1[CH2:17][CH2:16][CH2:15][CH2:14][CH2:13]1

参加物

4

反応物 1

HCID 232084362-(N-Benzyl-N-methylamino)-1-(N-piperidinyl)ethane

生成物 1

HCID 3157473Methyl(2-(piperidin-1-yl)ethyl)amine

試薬・触媒・溶媒 2

HCID 9942167Palladium hydroxide触媒HCID 702Ethanol溶媒

実験手順

A solution of the title compound of Step 11 (1.85 g, 7.96mmol) and 20% Pd(OH)2 on carbon in EtOH (50 mL) was placed under a hydrogen atmosphere (60 psi) at room temperature for 17 hours. The mixture was filtered and concentrated to give the title compound as a clear, yellow liquid (1.02 g, 90% crude yield). The proton spectral data were consistent with the proposed structure.

後処理

  1. customat room temperature
  2. customfor 17 hours
  3. filtrationThe mixture was filtered
  4. concentrationconcentrated

出典と根拠

ORDレコード
ord-24f9471b682b46ea902a3d42b6b01974
出典データセット
uspto-grants-1993_05
特許番号
US05212185

関連ノート

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