Methylamine → 2-Amino-4-methylamino-6-trifluoromethoxy-1,3,5-triazine
反応式
[CH3:1][NH2:2].[NH2:3][C:4]1[N:9]=[C:8](F)[N:7]=[C:6]([O:11][C:12]([F:15])([F:14])[F:13])[N:5]=1>O1CCCC1>[NH2:3][C:4]1[N:9]=[C:8]([NH:2][CH3:1])[N:7]=[C:6]([O:11][C:12]([F:15])([F:14])[F:13])[N:5]=1参加物
4
反応条件
- 温度
- 22 °C
実験手順
3.5 g (0.111 mol) of methylamine were passed over the course of 20 minutes into a stirred solution of 11 g (0.055 mol) of 2-amino-4-fluoro-6-trifluoromethoxy-1,3,5-triazine in 150 ml of tetrahydrofuran at 0° C. The mixture was stirred at 0° C. for one hour and at 22° C. overnight. It was then concentrated under reduced pressure, stirred with water and dried. 10.8 g (93.1% of theory) of the title compound of melting point 155°-157° C. (decomposition) were obtained.
後処理
- concentrationIt was then concentrated under reduced pressure
- stirringstirred with water
- customdried
出典と根拠
- ORDレコード
- ord-4883973c9e424028822a9b0323f9186e
- 出典データセット
- uspto-grants-1993_05
- 特許番号
- US05214143
反応ノート
読み込み中…