2-Chloro-5-(chloromethyl)pyridine → N-((2-Chlorothiazol-5-yl)methyl)ethanamine

HRID 249501

反応式

HRID 249501 の反応式
[Cl:1][C:2]1[S:3][C:4]([CH2:7]Cl)=[CH:5][N:6]=1.ClC1[N:15]=[CH:14][C:13](CCl)=CC=1>C(Cl)Cl>[Cl:1][C:2]1[S:3][C:4]([CH2:7][NH:15][CH2:14][CH3:13])=[CH:5][N:6]=1

参加物

4

反応物 2

HCID 1554792-Chloro-5-(chloromethyl)pyridineHCID 27631792-Chloro-5-chloromethylthiazole

生成物 1

HCID 22450338N-((2-Chlorothiazol-5-yl)methyl)ethanamine

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒

実験手順

The reaction procedure of Reference Example 17 was repeated except that crude 2-chloro-5-chloromethylthiazole was used in lieu of 6-chloro-3-pyridylmethyl chloride and that CH2Cl2 was used as the extractant. The procedure gave the title compound as a crude oil.

後処理

  1. customThe reaction procedure of Reference Example 17

出典と根拠

ORDレコード
ord-eef47cd986ac4f6abf30eb8c55e6c572
出典データセット
uspto-grants-1993_05
特許番号
US05214152

関連ノート

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