Water → HCID 86632552、化合物

HRID 251974ノート

反応式

HRID 251974 の反応式
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([Cl:8])[C:3]=1[N:9]1[CH:13]=[CH:12][CH:11]=[C:10]1[CH:14]=[O:15].[Br:16]N1C(=O)CCC1=O.O>CN(C)C=O>[Br:16][C:12]1[CH:11]=[C:10]([CH:14]=[O:15])[N:9]([C:3]2[C:4]([Cl:8])=[CH:5][CH:6]=[CH:7][C:2]=2[Cl:1])[CH:13]=1

参加物

5

反応物 3

HCID 962WaterHCID 67184N-bromobutanimideHCID 57780058HCID 57780058、化合物

生成物 1

HCID 86632552HCID 86632552、化合物収率 98.4%

試薬・触媒・溶媒 1

HCID 6228Dimethylformamide溶媒

実験手順

In 10 ml of N,N-dimethylformamide was dissolved 0.65 g of 1-(2,6-dichlorophenyl)-1H-pyrrole-2-carbaldehyde, and then 0.53 g of N-bromosuccinimide was added thereto. The mixture was stirred at room temperature for 1 hour. Water was poured into the reaction mixture, a deposited precipitate was collected by filtration to obtain 0.85 g of 4-bromo-1-(2,6-dichlorophenyl)-1H-pyrrole-2-carbaldehyde of the formula:

後処理

  1. filtrationa deposited precipitate was collected by filtration

出典と根拠

ORDレコード
ord-833c20d2dcc14ffc9cf4e67701b05a86
出典データセット
uspto-grants-2011_01
特許番号
US07867949B2

反応ノート

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