Water → HCID 86632556、化合物
反応式
[Cl:1][C:2]1[C:7]([N:8]2[CH:12]=[CH:11][CH:10]=[C:9]2[CH:13]=[O:14])=[CH:6][CH:5]=[CH:4][N:3]=1.[Br:15]N1C(=O)CCC1=O.O>CN(C)C=O>[Br:15][C:11]1[CH:10]=[C:9]([CH:13]=[O:14])[N:8]([C:7]2[C:2]([Cl:1])=[N:3][CH:4]=[CH:5][CH:6]=2)[CH:12]=1参加物
5
実験手順
To a solution of 6.05 g of 1-(2-chloro-3-pyridinyl)-1H-pyrrole-2-carbaldehyde in 20 ml of N,N-dimethylformamide was added 5.72 g of N-bromosuccinimide. The resulting mixture was stirred at room temperature for 1 hour. Water was poured into the reaction mixture, and a deposited precipitate was collected by filtration to obtain 4.22 g of 4-bromo-1-(2-chloro-3-pyridinyl)-1H-pyrrole-2-carbaldehyde of the formula:
後処理
- filtrationa deposited precipitate was collected by filtration
出典と根拠
- ORDレコード
- ord-0d886741c9c24ae6a6a1b02dabb9aab2
- 出典データセット
- uspto-grants-2011_01
- 特許番号
- US07867949B2
反応ノート
読み込み中…