4-Methylbenzaldehyde → 2-(4-Methylphenyl)-4-iodomethyl-5-methyloxazole

反応式

[I:1][CH2:2][C:3]1[N:4]=[C:5]([C:14]2[CH:19]=[CH:18][C:17]([CH3:20])=[CH:16][CH:15]=2)[O:6][C:7]=1[C:8]1C=CC=CC=1.C/C(/C(C)=O)=N\O.C1(C)C=CC(C=O)=CC=1>>[I:1][CH2:2][C:3]1[N:4]=[C:5]([C:14]2[CH:19]=[CH:18][C:17]([CH3:20])=[CH:16][CH:15]=2)[O:6][C:7]=1[CH3:8]

参加物

反応物 3

HCID 77254-Methylbenzaldehyde

HCID 64096332,3-Butanedione monoxime

HCID 574345044-Iodomethyl-5-phenyl-2-p-tolyloxazole

生成物 1

HCID 219803112-(4-Methylphenyl)-4-iodomethyl-5-methyloxazole

実験手順

Analogously to the building block synthesis of 4-iodomethyl-5-phenyl-2-p-tolyloxazole, diacetylmonoxime and p-tolualdehyde gave 4-iodomethyl-5-methyl-2-p-tolyloxazole.

出典と根拠

ORDレコード: ord-f34cf93ca45e470aa911036979a4d46e
出典データセット: uspto-grants-2011_01
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US07872034B2

反応ノート

読み込み中…