Trichloroisocyanuric Acid → 2-(3-Chloro-2-ethyl-6-fluoro-benzyl)-1H-imidazole
反応式
[Cl:1][C:2]1[C:3]([CH2:15][CH3:16])=[C:4]([C:11]([F:14])=[CH:12][CH:13]=1)[CH2:5][C:6]1[NH:7][CH2:8][CH2:9][N:10]=1.C1(N(Cl)C(=O)N(Cl)C(=O)N1Cl)=O.C1CCN2C(=NCCC2)CC1>>[Cl:1][C:2]1[C:3]([CH2:15][CH3:16])=[C:4]([C:11]([F:14])=[CH:12][CH:13]=1)[CH2:5][C:6]1[NH:10][CH:9]=[CH:8][N:7]=1参加物
4
実験手順
2-(3-Chloro-2-ethyl-6-fluoro-benzyl)-1H-imidazole was prepared from 2-(3-chloro-2-ethyl-6-fluoro-benzyl)-4,5-dihydro-1H-imidazole (Example 198), TCCA and DBU in analogy to Example 194e): light yellow crystals; MS (ISP): 241.2 ([M+H]+, 58%), 239.2 ([M+H]+, 100%).
出典と根拠
- ORDレコード
- ord-348278992a094d91904c1c1453a0cfa2
- 出典データセット
- uspto-grants-2011_01
- 特許番号
- US07875645B2
反応ノート
読み込み中…